NOT KNOWN FACTS ABOUT NUCYNTA TAPENTADOL

4.4 Exclusive warnings and safety measures to be used Tolerance and Opioid Use Disorder (abuse and dependence) Tolerance, Actual physical and psychological dependence, and opioid use ailment (OUD) might acquire on recurring administration of opioids. Abuse or intentional misuse of opioids may possibly end in overdose and/or death. The potential ris